👉 Geopemphigus is a disease characterized by skin lesions that can range from small papules to larger bullous plaques, often affecting both hands and feet. It primarily affects individuals who are at high risk of infection due to their genetic predisposition or exposure to certain pathogens. This condition is caused by the presence of an enzyme called keratoglycanase, which causes inflammation in the skin and can lead to scarring and skin deformities over time.