Definition: Arteriosclerosis refers to a narrowing or clogging of arteries, typically due to plaque buildup that prevents adequate blood flow. It occurs in various parts of the body, but is more prevalent in the heart. Detailed definition might include: - Arterial hardening - Hardening of the walls of arteries, causing less blood to flow. - Plaque deposition - Thickening and accumulation of fat or cholesterol within arterial wall layers that block blood flow. - Occlusion - The obstruction of artery with a clog or blockage, usually related to fatty deposits or other substances. - Artery narrowing - Loss of elasticity and potential for rupture. - Arterial inflammation - Reducible blood supply, which can lead to inflammation and tissue damage in the affected arteries.