Definition: Anticoagulin, also known as ATII (Adeco-Flanin II) and Amiloride, is a medication used to prevent blood clots in people with high blood pressure or certain heart conditions. The drug works by inhibiting the enzyme that causes blood to clot, preventing blood from flowing back into the body. This can help lower blood pressure and reduce risk of stroke, heart attack, and other types of strokes. It's usually taken by mouth, but some people might take it through a nasal spray or intravenous (IV) injection.