👉 Transcript engineering is a process that involves the manipulation and optimization of transcript sequences, typically in the context of bioinformatics and synthetic biology. It focuses on altering the nucleotide sequences of RNA molecules to achieve desired functional outcomes, such as enhancing gene expression, modifying protein function, or creating novel RNA-based therapeutics. This can be accomplished through various techniques, including CRISPR-Cas systems for precise editing, chemical modifications to improve stability or specificity, and computational design to predict and optimize RNA structures. The goal is to tailor RNA transcripts for specific applications, ranging from basic research to advanced medical treatments, by ensuring they perform optimally within biological systems.