👉 Must-infection refers to a condition where an individual is already infected with a pathogen and has no effective means of preventing further disease progression or transmission. This state is critical because it means the host's immune system is compromised or unable to control the infection, often due to underlying health conditions, immunosuppression, or exposure to high pathogen loads. In such cases, the infection can spread rapidly, leading to severe complications and potentially fatal outcomes if left untreated. Preventing the spread of the pathogen to others and managing symptoms become paramount, as the infected individual's body is no longer capable of containing the infection effectively.