👉 Fluphenazine is a chemical compound that belongs to the family of flavone alkaloids. It has been used historically as an antipyretic, analgesic, and anti-inflammatory agent. Fluphenazine compounds are known for their ability to inhibit the enzyme cytochrome P450 2C9, which plays a crucial role in the metabolism of drugs and can lead to adverse effects if not properly regulated. Fluphenazine was first isolated from the bark of the