👉 Biguanides are a type of nonsteroidal anti-inflammatory drug (NSAID) that act by inhibiting prostaglandin synthesis in the body. They work by blocking the action of the prostaglandins, which are chemicals produced by cells to help maintain tissue integrity and protect against injury. These drugs can be found in over-the-counter medications such as ibuprofen, naproxen, or celecoxib (Celebrex), among others. The exact mechanism by which big