👉 In research design, a preconfound is an effect that can be explained by other factors. It's a condition where one factor influences another without any direct interaction between them. For example, if you have two independent variables (X and Y) and you want to test whether X causes Y, the preconfound would be the difference in the values of X and Y before treatment. In other words, it's an effect that can't be explained by the treatment or the other factors.