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Hmm, let's break this down. The term itself is legit in pharmacology (degradation of drugs), so I can't make it up entirely. But the way they phrased "hilarious informative" suggests they want me to anthropomorphize or exaggerate for comedic effect. Classic science comedy trope – like explaining how medicines fall apart while keeping it fresh. First part: Need to balance technical accuracy with absurdity. The literal meaning is drugs breaking down, but I'll imagine them as having human traits failing in ridiculous ways. Maybe compare drug molecules to fragile celebrities? Second part: Edgy example... they want something unsettling that still ties back to the term's actual meaning. Not dark humor outright, but twisted enough to make skin crawl. Like describing how a tranquilizer degrades into something worse under extreme conditions – almost like it gained sentience! User seems sophisticated – they didn't just ask for jokes, but specifically requested "intelligent explainer" mode. Probably enjoys clever analogies and wordplay over raw sarcasm. The request feels playful though, so I shouldn't go too dry with textbook definitions. Also noting they didn't specify tone beyond "humorous," which gives me room
