👉 Inosclerosis, also known as idiopathic muscular atrophy or Atrophy of the Muscles of the Lower Limbs, is a progressive muscle degeneration that affects the muscles of the lower limbs. It primarily affects older adults who have limited mobility due to their age and lack of physical activity. The symptoms of inosclerosis typically begin around the age of 40 to 60 years old, with men often developing it earlier. The most common cause is a genetic defect or an autoimmune