👉 Indaconitine is a naturally occurring compound that is derived from the bark of the Indian coniferous tree, Populus tremula. It was first isolated in 1936 and recognized as an organic acid by Dr. Robert A. Burt in 1952. Indaconitine has been studied for its potential health benefits due to its ability to inhibit the production of inflammatory cytokines from immune cells, which may contribute to a variety of conditions such as rheumat