Definition: N.S. Wales is one of 32 Welsh-speaking regions in the United Kingdom, located primarily along the River Severn bordering England with England's South Wales region. It is bounded by the English Channel to the north, North Wales to the west and south, and Cornwall to the east. The word 'N.S.' refers to Nantwich, a city on the river Severn in Shropshire, England which is home to the National Science and Technology Centre (NSTC), one of the UK's leading research institutions. The N.S. Wales is a region where Welsh-speaking people live, work, and attend university. Definition: The term 'N.S.' refers to Nantwich, a city on the River Severn in Shropshire, England which is home to the National Science and Technology Centre (NSTC). It is also referred to as Shropshire's City of Knowledge.