Definition: Protodermal is a concept in embryological science that refers to the development of an embryo's innermost layer, which serves as the initial stage or stage of organ formation. Protodermal cells are the most primitive cells that develop into the body and the first organs. These cells include mesenchymal cells, which are specialized for their role in maintaining the structure and function of the organism, and protoderm cells, which are responsible for forming the extracellular matrix (ECM) around
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