Definition: Prionodesmaceous is a term used in the field of molecular biology, specifically in the study of prions and their role in disease. Prions are proteins that can cause various diseases such as Creutzfeldt-Jakob Disease (CJD) and Alzheimer's Disease. The term "prionodesmaceous" refers to the unique structure of prion particles that makes them appear like small, porous, or smelly dust-like substances.