Definition: Nonprescription (NP) drugs are prescription drugs that are not prescribed by a healthcare provider and can be obtained without a doctor's prescription. These include over-the-counter medications such as vitamins, supplements, and painkillers, which may be available through pharmacies or online at the click of a button. Nonprescription drugs are often less expensive than prescription drugs and have fewer side effects, but they should not be used in place of medical care.