Definition: Nephrocoloptosis is a medical condition that causes small, round, and often yellowish-nodular swellings or nodules on the skin. These lesions are typically found in the kidneys, but they can also occur elsewhere in the body. The exact cause of nephrocoloptosis is not fully understood, but it is believed to be related to a genetic mutation or an autoimmune response. Nephrocoloptosis is often associated with other conditions such as diabetes and kidney disease