Definition: Metapleural is a term used in medicine to describe conditions where nerve cells or ganglia are placed between two layers of tissue, such as the lining of blood vessels. This can occur in the brain, spinal cord, and other parts of the body. In some cases, metapleural disease may be caused by tumors that invade the nerve cells or ganglia, leading to abnormal communication between them. These conditions are not a normal part of the body's natural response to injury or infection
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