Definition: The word 'HRP19' refers to the human leukocyte antigen class I molecule, a part of the immune system that allows cells in our bodies to recognize and respond to foreign antigens such as pathogens. This molecule is encoded by chromosome 2c, which is found on the Y chromosome. It plays a crucial role in cell signaling and plays a fundamental role in immune function, helping protect the body from infection and inflammation. The detailed definition of 'HRP19' includes: - It's an antigen specific receptor on the human leukocyte (HLA) complex, a class I molecule recognized by other cells to allow their recognition of pathogen antigens. This is one way in which our immune system identifies and responds to foreign substances. - The HRP19 gene encodes for a part of this complex called the immunoglobulin superfamily that consists of various proteins involved in innate immunity, such as MHC molecules, B cell receptors, complement proteins, and type I IFN, a cytokine that helps maintain homeostasis by signaling immune cells to release inflammatory mediators. - The term 'human leukocyte antigen' (HLA) refers to a group of proteins distributed throughout the human body. HLA is involved in determining whether an individual has immunity against particular pathogens or not, and it can be used as a biomarker for different types of cancer and other diseases. This information highlights the crucial role that the HRP19 molecule plays in our immune system's defense mechanism against invading pathogens, and how it allows cells to recognize and respond accordingly.

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