Definition: Hemimellitene is a type of glycosaminoglycans found in the skin and connective tissues. It is composed of four linked chains, each with six monomeric units, which are bound together by a disulfide bond. This structure allows for the formation of structures such as keratinocytes, collagen fibers, and elastin. Hemimellitene plays an important role in maintaining the integrity of these tissues and may also play a role in wound healing