Definition: Carpocephalum is a term used in medicine to describe a condition where the brain and spinal cord are malformed. It can cause problems with movement, speech, and breathing. Common examples of carpocephalic malformations include spina bifida, which is caused by an abnormal development of the spine, and trisomy 13, also known as Down syndrome. These conditions can lead to developmental delays and difficulty with physical activities such as walking or talking.