Definition: Calciphylaxis is a medical condition characterized by inflammation of the skin, particularly on the palms and soles. It can be caused by a variety of factors such as allergies or infections, but it is most commonly associated with the use of certain medications that cause an allergic reaction. Calciphylaxis can lead to severe pain, swelling, itching, and redness around the affected areas, which can make them uncomfortable to touch and difficult to wear shoes or clothing due to their appearance. Calciph