Definition: Barbitalism is a type of barbiturate drug that was first developed in 1960s and was used to treat conditions such as delirium tremens, psychosis, and depression. It contains barbiturates (such as chlorpromazine) mixed with anesthetic drugs and other substances that are intended to produce hallucinations or a sense of detachment from reality. The drug has been associated with abuse, particularly among young people, who may use it in self-medication