Definition: Annelism, in the Bible, means a person's heart or soul that has been corrupted by sin or evil, often referring to someone who has lost their spiritual integrity or faithfulness. It appears in 2 Kings 19:7 as the Holy Spirit speaking to the prophet Elisha and instructing him, "I am the Lord, I have set a spirit in you." The word comes from an ancient Greek term that means "heart disease" and "inability to perform normal functions of the soul."