Definition: The word "achondrism" refers to a type of bone, called an achondroplasia, which is characterized by the development of bone marrow in excess, resulting in increased osteoid production and reduced trabecular bone density. Achondrism can occur in both children and adults. It occurs when the bones are unable to grow properly or develop properly, leading to a weakened or diseased bone that may be brittle or fragile. The normal development of bone is dependent on specific factors such as blood supply, nutrient levels, and cell activity. When these conditions are disrupted or absent, bone marrow can accumulate at a rapid rate, which results in increased osteoid production and decreased trabecular bone density. Achondrism affects multiple bones, including the long bones (like the femur, tibia, and calcaneus) as well as short bones (such as the wrist, elbow, shoulder, pelvis) that are not normally formed. This can lead to a loss of bone strength, reduced mobility, and increased risk of fractures. Achondrism is characterized by signs like bruising or bleeding from cuts, changes in blood vessels, pain during movement, and stiffness or discomfort around the bone areas. It often occurs when the bones are not properly formed or the bones are too small to grow properly. The term "achondrism" is used in medical context to describe this condition in children and adults, as well as to help diagnose it in patients who present with signs of bone marrow overproduction. In summary, achondrism refers to a type of bone development that occurs when the bones are unable to grow properly or develop properly due to excessive production of marrow. It is characterized by increased osteoid production and decreased trabecular bone density.

achondritic