Definition: The word "aminoglutaric" refers to a specific type of compound in which the carbon atom of an amino acid (such as glutamine, leucine, or cysteine) has been replaced with a different group, such as a thiol group (a group that can donate protons), and an amine group. The term "aminoglutaric" is often used to describe compounds where the carbon atoms of an amino acid have been replaced with a group called a thiol or amine. Here are some examples of what amino acids might be substituted for: 1. Glutamine (Glu): Amino Acid: Glu, glutamate. Synthetization Process: - The amino group is lost due to the protonation of the sulfur atom from the hydrogen atom in the amine group. 2. Leucine (Leu): Amino Acid: Leu, leucine. Synthetization Process: - The amide group is replaced by a thiol group, making leucine into cysteine. 3. Cysteine (Cys): Amino Acid: Cys, cysteine. Synthetization Process: - The amino group is replaced with an amine group, which makes the protein denatured and non-proteinaceous. The term "aminoglutaric" suggests that these compounds are produced by enzymatic reactions where a group of amino acids are converted into thiol or amide groups through the action of a catalyst. This process allows for the formation of other amino acids from thiol or amine groups, such as glutamine and cysteine.
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