Definition: The Human Papillomavirus Bivalent (Types 16, 18) Vaccine, also known as HPV Vax-BV or HPV Vax-Ab, is a vaccine intended to prevent the spread of sexually transmitted infections such as HPV from one person to another. ## Key Terms •

Human papillomavirus:

A family of viruses that cause cancer in the reproductive tract. Common causes include cervical, anal, and vulval cancers. •

Vaccine:

A drug or other substance used to protect an individual against a particular disease or condition. •

Type 16:

This vaccine is not a specific subtype but a term describing the general type of HPV found in many types. •

Type 18:

This vaccine is not a specific subtype but a term describing a different variant of HPV from Type 16. ## Key Components ### Vaccine The Human Papillomavirus Bivalent (Types 16, 18) Vaccine (HPV Vax-BV or HPV Vax-Ab) consists of an intramuscular (IMU) dose consisting of two separate immunogenic doses: a vaccine and a booster. ### Immunization Sequence There are two different sequence types for this vaccine: •

Type 1:

This type is given as one dose before the second dose, which results in immediate protection against both types. The second dose must be administered at least 6 weeks after vaccination. •

Type 2:

This type is given once a week for the first three months of life and every six months thereafter, resulting in lifelong immunity. ## Definition ### Vaccine The Human Papillomavirus Bivalent (Types 16, 18) Vaccine is a vaccine designed to prevent the transmission of sexually transmitted infections (STIs) from one person to another, including cervical cancer.

Human Papillomavirus Bivalent (Types 16, 18) Vaccine, Recombinant