Definition: Dengue Tetravalent Vaccine: A vaccine that contains 4 different antibodies from the four major types of dengue viruses: Dengue A, B1, C1-2, and D. Live Dengue Tetravalent Vaccine is a live attenuated form of Dengue Tetravalent Vaccine. It is considered to be safe and effective in preventing dengue fever. In the live vaccine formulation, 4 different antibodies from the four major types of dengue viruses (D1-D4) are genetically encoded into a single gene, allowing for rapid production of these antibodies without requiring further processing or storage. The immune system then recognizes and neutralizes the virus through its specific receptors. The Live Dengue Tetravalent Vaccine is typically given by oral administration and can be administered at any time during the child's life to protect them from dengue fever. However, the effectiveness of this vaccine may vary depending on factors such as the child's age, health status, and vaccination history. It's important to note that while live vaccines are generally safe and effective for preventing severe forms of dengue (dengue hemorrhagic fever), they can still cause mild symptoms such as muscle pain or headache. If a child exhibits any signs of dehydration or other serious complications, it's crucial to seek medical attention immediately. Overall, the Dengue Tetravalent Vaccine is an essential tool in preventing severe dengue outbreaks and maintaining public health by minimizing the risk of serious complications due to the high fever response to dengue.
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