Definition: The word "Applacentalia" is a term in medical literature that refers to the first placenta, or initial fetal lung, formed during pregnancy. It's also known as the primary placenta. This tissue is responsible for delivering oxygen and nutrients to the developing baby. The primary placenta develops from the endometrium (uterine lining), which starts before implantation but begins to form around the 20th week of gestation. The word 'Aplacentalia' was first used in medical literature by William J. Nadel in 1968 when he described it as "the most advanced fetal lung". This term was coined after a study examining the development of fetal lungs in rats with congenital abnormalities, which demonstrated that it appeared to be the most developed one.
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