👉 Prothrombin is a protein that in humans plays a critical role in the activation of the clotting system. It is responsible for activating the blood coagulation cascade, which results in the formation of thrombi (blood clots). Prothrombin is produced by the liver and is an essential component of the body's immune response to external stimuli such as bleeding. Prothrombin can be synthesized from a variety of sources including blood plasma and red blood cells. In some individuals,
