👉 Febricitants are a class of medications used to treat inflammatory bowel disease (IBD) by blocking the production of prostaglandins, which are produced in response to inflammation. They work by inhibiting the actions of prostaglandin D2, an enzyme that is involved in the synthesis and release of prostaglandins from blood vessels. Febricitants can be classified into two main categories: non-steroidal (NSAIDs) and proton pump inhibitors (PPI