👉 Human experimentation has historically involved unethical practices such as the Tuskegee syphilis study, where African-American men were misled and denied treatment for syphilis, or the Nazi experiments during World War II that conducted horrific atrocities on prisoners of war and concentration camp victims. Modern human experimentation adheres to strict ethical guidelines and is subject to rigorous oversight by institutions such as institutional review boards (IRBs), aiming to ensure participants' safety and rights are protected while advancing medical knowledge and treatments.