👉 Velvet infection, also known as human granulomatosis with polyangiitis (HGP-A), is a rare, chronic inflammatory disease primarily affecting small blood vessels, particularly in the lungs, kidneys, and other organs. It is characterized by the formation of granulomas—clusters of immune cells—and vasculitis, where the blood vessels become inflamed and damaged. This condition can lead to a range of symptoms, from mild respiratory issues to severe complications like kidney failure and vision loss. The exact cause is unknown, but it is thought to involve an abnormal immune response, possibly triggered by infections or genetic predispositions. Treatment often focuses on managing inflammation and preventing organ damage, typically involving immunosuppressive medications and sometimes biologics.
