👉 Human experimentation has a long and controversial history that includes both groundbreaking medical research, like the Tuskegee Syphilis Study, which aimed to observe the natural progression of untreated syphilis in African-American men without their consent, as well as more recent studies on drugs or medical devices that have raised serious ethical concerns for violating participants' rights and wellbeing. These experiments often led to significant advances in science and medicine but also underscored the critical importance of informed consent and protecting human subjects' welfare.