👉 Tier medical research is conducted to establish the safety and efficacy of new treatments, drugs, or medical devices before they are allowed to be used in clinical trials on humans. It typically progresses through three levels: Tier I involves preliminary studies with healthy volunteers, Tier II includes small-scale studies with patients to assess safety and dosage, and Tier III is large-scale studies that further evaluate the treatment's effectiveness and monitor side effects before it reaches the final stages of clinical trials.