👉 Rat engineering is an advanced biotechnological field that involves the genetic modification of rats to study human diseases, develop new therapies, and test medical treatments in a controlled environment. Scientists use techniques like CRISPR-Cas9 to introduce, delete, or alter specific genes within the rat genome, creating transgenic rats that mimic human genetic conditions. These engineered rats serve as valuable models for understanding complex diseases such as cancer, diabetes, and neurological disorders. By observing the effects of genetic modifications on rat physiology and behavior, researchers can gain insights into disease mechanisms and evaluate the efficacy and safety of potential treatments before human trials. This approach not only accelerates drug development but also reduces ethical concerns associated with using human subjects in early-stage research.