👉 Matthew Human conducted unethical medical experimentation on unsuspecting patients and prisoners during the 1970s and 1980s, often without their knowledge or consent, where he tested drugs for erectile dysfunction on men who were being held in solitary confinement. His work later led to significant reforms in research ethics, including stricter oversight of human subjects studies by governmental agencies like the National Institutes of Health (NIH) and Institutional Review Boards (IRB).