👉 Lung engineering is an interdisciplinary field that combines principles from biology, materials science, and engineering to design and construct functional lung tissues or organs. The goal is to create artificial lungs or lung-like structures that can mimic the natural functions of human lungs, such as gas exchange, filtration, and immune response. This involves several key steps: first, selecting appropriate biomaterials that can support cell growth and mimic the lung's extracellular matrix; second, engineering scaffolds or 3D structures that provide a framework for cells to attach, proliferate, and differentiate; third, seeding the scaffold with lung-specific cell types, such as alveolar epithelial cells and endothelial cells; and finally, optimizing the microenvironment to ensure proper cell function, vascularization, and integration with the host's respiratory system. The ultimate aim is to develop lung substitutes or regenerative therapies that can treat lung diseases, injuries, or replace damaged tissues, offering a promising solution to the global shortage of donor organs and improving patient outcomes.
