👉 The London Project to Edit the Human Genome (LPEHG) was a pioneering initiative launched in 2015 by a coalition of scientists, ethicists, and policymakers to explore the feasibility and ethical implications of using CRISPR-Cas9 gene-editing technology for human germline modifications. The project aimed to create a detailed, publicly accessible database of edited human embryos to advance research on genetic diseases and improve gene-editing techniques. However, it faced significant ethical opposition due to concerns about safety, consent, and the potential for unintended consequences or "designer babies." Despite its ambitious goals, the project ultimately ceased operations in 2018 due to these ethical challenges and a lack of consensus on how to proceed with human germline editing.