👉 H-infection, also known as heterologous infection, is a phenomenon where an immune response against one pathogen inadvertently enhances the susceptibility or severity of another, unrelated pathogen infection. This occurs because the immune system's activation, often through the production of antibodies or inflammatory responses, can create an environment that facilitates the entry, replication, or spread of the secondary pathogen. For example, vaccination against one virus might weaken the immune system's ability to combat a different virus, or the inflammation caused by one infection can damage tissues in a way that makes them more vulnerable to another. This interaction highlights the complex and sometimes counterintuitive nature of the immune system.
