👉 Edwards' infection, also known as Edwards syndrome or Edwards villopathy, is a rare congenital disorder characterized by severe developmental abnormalities primarily affecting the heart, brain, and other organs. It results from mutations in the NES (Neonatal Ephelides Syndrome) gene, which is crucial for proper cell signaling during embryonic development. This genetic defect leads to the underdevelopment or absence of certain structures, particularly the heart, causing congenital heart defects such as ventricular septal defects and tetralogy of Fallot. Additionally, neurological issues like microcephaly, intellectual disability, and seizures are common. The syndrome is typically diagnosed in newborns through a combination of prenatal screening and postnatal clinical evaluation, with no cure but management strategies focusing on supporting affected infants to improve their quality of life.
