👉 Dose math is the quantitative calculation of the amount of a drug or treatment administered to achieve a desired therapeutic effect while minimizing potential side effects. It involves understanding the relationship between the dose (amount of drug), the body's response (e.g., efficacy or toxicity), and the patient's individual characteristics like weight, age, and organ function. Key concepts include the effective dose (ED50), which is the dose required to produce a desired effect in 50% of the population, and the therapeutic index (TI), which measures the safety margin by comparing the dose that produces toxicity to the dose that is therapeutic. Dose math often employs pharmacokinetic and pharmacodynamic principles to optimize dosing regimens, ensuring that patients receive the right amount of medication at the right time for maximum benefit with minimal risk.
