👉 The Crawford infection, also known as Crawford's syndrome or Crawford's disease, is a rare and often fatal condition characterized by severe systemic inflammation and multiorgan dysfunction. It typically arises from an infection, most commonly bacterial, but can also result from fungal or viral sources. The infection triggers a hyperinflammatory response, leading to widespread vasculitis (inflammation of blood vessels), coagulopathy (abnormal blood clotting), and organ failure. This can affect multiple systems, including the lungs, kidneys, liver, heart, and brain, causing symptoms such as fever, hypotension, organ dysfunction, and in severe cases, death. The exact mechanisms linking the infection to this severe inflammatory response are not fully understood but involve complex interactions between the immune system and pathogens.
