👉 Compressed infection, also known as a biofilm-associated infection, occurs when bacteria form a structured community embedded in a protective extracellular matrix, often within medical devices or tissues. This environment shields the bacteria from the host's immune system and antibiotics, making infections more difficult to treat. The matrix, composed of polysaccharides, proteins, and DNA, provides structural integrity and facilitates nutrient exchange and communication among the bacterial cells. As a result, compressed infections can persist despite standard antibiotic therapies, leading to chronic or recurrent infections that are challenging to eradicate. Understanding this mechanism is crucial for developing new strategies to combat these resilient pathogens.
