👉 The clearing fluid, also known as hyaluronidase or hyaluronate lyase, is a substance used in medical procedures to facilitate the spread of fluids and cells within tissues. It works by breaking down hyaluronic acid, a major component of the extracellular matrix that acts as a natural glue holding tissues together. By degrading this substance, the clearing fluid increases tissue permeability, allowing for better distribution of injected solutions, such as contrast agents or medications, and enhancing the effectiveness of treatments like biopsies and tumor ablations. This process is crucial in ensuring that the medical interventions reach their intended targets efficiently and accurately.