👉 The Clarke-Infection model, often referred to as the Clarke-Infection theory, is a mathematical framework used to describe the spread of infectious diseases within a population. Developed by John Clarke and others, this model extends the basic SIR (Susceptible-Infected-Recovered) model by incorporating factors that influence transmission dynamics, such as contact rates and the rate at which susceptible individuals become infected. The model considers a population divided into three compartments: those who are susceptible to infection, those who are infected and can transmit the disease, and those who have recovered and are immune (though not always explicitly modeled as immune from the start). By introducing parameters that reflect the frequency of contacts between individuals and the probability of transmission upon contact, the Clarke-Infection model provides a more nuanced understanding of how infections spread, particularly in heterogeneous populations where contact patterns vary. This approach helps in predicting the impact of interventions like social distancing or vaccination on disease dynamics.