👉 The term "cage" in the context of infection refers to an environment where pathogens are confined and protected, often leading to persistent or recurrent infections. This can occur when bacteria form biofilms—complex communities encased in a protective matrix of extracellular polymeric substances—that shield them from host defenses and antibiotics. Within these biofilms, bacteria can exchange genetic material, enhancing their resistance to treatment and making them more resilient. The "cage" metaphor aptly captures how pathogens can become isolated and fortified, evading immune responses and conventional therapies, thereby complicating infection control and treatment strategies.
