👉 Bulk-infection is a phenomenon where a large number of pathogens overwhelm a host's immune system, leading to a rapid and often severe infection. This occurs when the pathogen load exceeds the host's capacity to mount an effective immune response, resulting in widespread tissue damage and systemic inflammation. The immune system, initially attempting to contain the infection, can become overwhelmed, leading to conditions such as sepsis, where the infection spreads throughout the body via the bloodstream. This overwhelming scenario can be exacerbated by factors like a compromised immune system, high pathogen virulence, or the presence of multiple pathogens, all of which contribute to the rapid progression and severity of the infection.
