👉 The B research, or the B cell receptor (BCR) repertoire analysis, is a method used to study the diversity and specificity of B cells within an individual's immune system. It involves sequencing the variable regions of BCRs, which are the parts of antibodies that recognize and bind to specific antigens. By analyzing these sequences, researchers can map out the unique BCRs present in a sample of B cells, providing insights into the immune response to various pathogens. This technique helps in understanding how the immune system generates a vast array of specific antibodies, identifies clonal expansions (where a subset of B cells proliferates in response to an antigen), and tracks changes in the B cell repertoire over time or across different conditions, such as infections or autoimmune diseases.
