👉 Pimples, medically known as acne, typically arise from a combination of factors including excess sebum production, clogged pores, bacterial infection, and inflammation. When hair follicles become blocked with dead skin cells and oil, bacteria like Propionibacterium acnes can proliferate, leading to inflammation and the formation of pimples. Hormonal changes, stress, genetics, and certain skincare products can also contribute to acne by exacerbating these conditions.