👉 Antiphrastic is a medication that blocks or reduces the effects of a certain neurotransmitter, such as GABA (gamma-aminobutyric acid), which plays a key role in regulating sleep. It works by blocking the action of this neurotransmitter on the brain's neurons, reducing or preventing the release of these neurons into the synaptic cleft, thereby inhibiting the transmission of sensory information to the brain. Antiphrastic drugs can be used for treating conditions such as narcolepsy